The literature on deep brain stimulation (DBS) and adaptive DBS (aDBS) raises concerns that these technologies may affect personality, mood, and behavior. We conducted semi-structured interviews with researchers (n = 23) involved in developing next-generation DBS systems, exploring their perspectives on ethics and policy topics including whether DBS/aDBS can cause such changes. The majority of researchers reported being aware of personality, mood, or behavioral (PMB) changes in recipients of DBS/aDBS. Researchers offered varying estimates of the frequency of PMB changes. A (...) smaller majority reported changes in personality specifically. Some expressed reservations about the scientific status of the term ‘personality,’ while others used it freely. Most researchers discussed negative PMB changes, but a majority said that DBS/aDBS can also result in positive changes. Several researchers viewed positive PMB changes as part of the therapeutic goal in psychiatric applications of DBS/aDBS. Finally, several discussed potential causes of PMB changes other than the device itself. (shrink)

The construct of cognitive moral development seemingly has powerful practical relevance in many areas of life. Nonetheless, moral reasoning seems of marginal relevance at best in the context of business ethics. Simply put, moral reasoning measurement indices are often only weakly related to many other apparently pertinent variables, and such findings cast doubt upon the construct validity of cognitive moral development. Many such unexpectedly weak relationships, however, may stem from two largely unrecognized methodological artifacts. The first artifact is an almost (...) total reliance on the P index of the Defining Issues Test (DIT) designed to assess moral development even when this index may be inappropriate in a particular context. A second artifact that seems particularly salient in the context of attitudes toward authority involves a not always appropriate reliance on samples that include respondents whose moral reasoning is uncoupled from their action choices. These artifacts may restrict the amount of variance explained in observed relationships, and thus constrain the potential for moral reasoning to understand and explain behavior and attitudes relevant in the context of business ethics. Researchers are urged to use DIT D scores (in addition to P scores) in specific situations, and to examine relationships among high DIT U scorers whose moral reasoning is tightly coupled with their action choices. The application of these guidelines may have profound implications for advancing our fundamental understanding of moral reasoning, and of increasing its relevance to business ethics. (shrink)

Publishing a collection of fragments from a classical author is a risky business: the moment the book appears in print, it may already be outdated, as new fragments could have come to light. Or, in the words of Ecclesiasticus 18:7: ‘When a man hath done, then he beginneth; and when he leaveth off, then he shall be doubtful’. The same fate befell me shortly after the publication of my collection of fragments from Rufus of Ephesus' On Melancholy. Manfred Ullmann wrote (...) to me that the late Rainer Degen had discovered a new fragment; in the course of my research, I came across some relevant quotations in the Hippocratic Treatments by the tenth-century author aṭ-Ṭabarī; and recently, Klaus-Dietrich Fischer published two related fragments. The following short note contains these new fragments together with an English translation and commentary. At the end, I also offer some addenda and corrigenda, partly in light of the reviews that have since appeared. (shrink)

Jones (1990) described ten workplace behaviors of a dubious ethical nature and determined that the hierarchical position adopted by respondents influenced the perceived acceptability of these behaviors. This measure seems promising, and therefore the purpose of this investigation is two-fold: (1) to explore further the psychometric properties of these ten items; and (2) to examine the role of individual difference variables as correlates of perceived acceptability. In two samples of working people, the Jones items were found to be internally consistent, (...) not obviously subject to range restriction, modestly related to social desirability, largely orthogonal to age and managerial status, but clearly linked with Machiavellianism. The nature of the linkage between perceived acceptability and both sex and the Protestant work ethic differed across the two studies, which underscores the need for future research. Two additional variables worth investigating in such research may be locus of control and equity sensitivity. (shrink)

The mere presence of irrelevant external stimuli results in interference with the fidelity of details retrieved from long-term memory (LTM). Recent studies suggest that distractibility during LTM retrieval occurs when the focus of resource-limited, top-down mechanisms that guide the selection of relevant mnemonic details is disrupted by representations of external distractors. We review findings from four studies that reveal distractibility during episodic retrieval. The approach cued participants to recall previously studied visual details when their eyes were closed, or were open (...) and irrelevant visual information was present. The results showed a negative impact of the distractors on the fidelity of details retrieved from LTM. An fMRI experiment using the same paradigm replicated the behavioral results and found that diminished episodic memory was associated with the disruption of functional connectivity in whole-brain networks. Specifically, network connectivity supported recollection of details based on visual imagery when eyes were closed, but connectivity declined in the presence of visual distractors. Another experiment using auditory distractors found equivalent effects for auditory and visual distraction during cued recall, suggesting that the negative impact of distractibility is a domain-general phenomenon in LTM. Comparisons between older and younger adults revealed an aging-related increase in the negative impact of distractibility on retrieval of LTM. Finally, a new study that compared categorization abilities between younger and older adults suggests a cause underlying age-related decline of visual details in LTM. The sum of our findings suggests that cognitive control resources, although limited, have the capability to resolve interference from distractors during tasks of moderate effort, but these resources are overwhelmed when additional processes associated with episodic retrieval, or categorization of complex prototypes, are required. (shrink)

Hippocrates is a towering figure in Greek medicine. Dubbed the 'father of medicine', he has inspired generations of physicians over millennia in both the East and West. Despite this, little is known about him, and scholars have long debated his relationship to the works attributed to him in the so-called 'Hippocratic Corpus', although it is undisputed that many of the works within it represent milestones in the development of Western medicine. In this Companion, an international team of authors introduces major (...) themes in Hippocratic studies, ranging from textual criticism and the 'Hippocratic question' to problems such as aetiology, physiology and nosology. Emphasis is given to the afterlife of Hippocrates from Late Antiquity to the modern period. Hippocrates had as much relevance in the fifth-century BC Greek world as in the medieval Islamic world, and he remains with us today in both medical and non-medical contexts. (shrink)

In an article published recently in theJournal of Business Ethics, Vitellet al. (1991) found that elderly respondents scored surprisingly high on a measure of Machiavellianism. This paper offers an alternative explanation for this unexpected result — it may be an artifact of the survey format employed — and recommends additional research to help clarify the issues raised by Vitell and his colleagues.

BackgroundThere is a growing interest in using cognitive–behavioural therapy (CBT) with people who have Asperger syndrome and comorbid mental health problems.AimsTo examine whether modified group CBT for clinically significant anxiety in an Asperger syndrome population is feasible and likely to be efficacious.MethodUsing a randomised assessor-blind trial, 52 individuals with Asperger syndrome were randomised into a treatment arm or a waiting-list control arm. After 24 weeks, those in the waiting-list control arm received treatment, while those initially randomised to treatment were followed (...) up for 24 weeks.ResultsThe conversion rate for this trial was high (1.6:1), while attrition was 13%. After 24 weeks, there was no significant difference between those randomised to the treatment arm compared with those randomised to the waiting-list control arm on the primary outcome measure, the Hamilton Rating Scale for Anxiety.ConclusionsTrials of psychological therapies with this population are feasible. Larger definitive trials are now needed. (shrink)

Ensemble musicians play in synchrony despite expressively motivated irregularities in timing. We hypothesized that synchrony is achieved by each performer internally simulating the concurrent actions of other ensemble members, relying initially on how they would perform in their stead. Hence, musicians should be better at synchronizing with recordings of their own earlier performances than with others’ recordings. We required pianists to record one part from each of several piano duets, and later to play the complementary part in synchrony with their (...) own or others’ recordings. The pianists were also asked to identify their own recordings. The pianists were better at synchronizing with their own than with others’ performances, and they were able to recognize their own recordings. Furthermore, synchronization accuracy and recognition were correlated: Pianists who were relatively accurate at synchronizing with their own performances were also good at recognizing them. Thus, action simulation may underlie both synchronization and self-recognition. (shrink)

When did historians begin to put quotation marks around the wordreal? There are many examples of this habit and some of them will be set forth as evidence in what follows. But before doing so we might ask a preliminary question: What are the quotation marksthemselvessupposed to mean? Today we find them so familiar they hardly need to be written and they are more frequently consigned to the everyday repertoire of silent gesture: two fingers on either hand clutch at the (...) air as if they meant to tickle the flanks of the invisible beast between them. The popular term is “scare-quotes,” a pun on the word “scarecrow.” Its etymology is revealing: just as a mere representation of a body in a field may scare off birds, so too scare-quotes permit someone to deploy a word without sincere commitment to what it normally means. But further reflection tells us that the effects are not so similar after all: To use a term without sincerity robs it of its original meaning and holds up its lifeless corpse to ridicule. The more knowing sort of crow can settle on the shoulder of the figure on the pole precisely because it recognizes that such a sorry excuse for a man can in fact harm no one. Similarly when one putsrealityin quotation marks we are put in mind of the living concept but we are immediately alerted to the fact that, for the user at least, the new term enjoys no metaphysical prestige. How did this happen? When and why did the single most privileged word in the entire lexicon of metaphysics begin to lose its authority such that in certain spheres of intellectual sophistication its sincere use would only seem an embarrassment and a sign of naïveté? (shrink)

An economic agenda, characterized by the mastery of subject knowledge or expertise, increasingly dominates higher education. In this article, I argue that this agenda fails to satisfy the full range of students’ aspirations, responsibilities and needs. Neither does it meet the needs of society. Rather, the overall purpose of higher education should be the morphogenesis of the agency of students, considered on an individual and on a collective basis. The article builds on recent critical realist theorizing to trace the generative (...) mechanisms that affect the morphogenesis of such agency. I argue that reflexive deliberation shapes the agency of students as they engage in teaching–learning interactions. It may be possible to enhance the agency of students if approaches are used that consider curricular knowledge, the presence of supportive social relations and the dedication of students. The article offers ways to promote the flourishing of students rather than their dehumanization. (shrink)

"Science and Theology in Descartes' Meditations on First Philosophy" has two primary goals. The first is to establish Descartes' understanding of the primary purpose of the Meditations . The second is to determine the meaning, status, and purpose of the fundamental Cartesian theological and scientific principles employed in the Meditations. ;Descartes makes two distinct and explicit statements of the primary purpose of the Meditations. The first statement, made in the dedicatory epistle to the Meditations, claims that the primary purpose of (...) the Meditations is to establish the truth of the Christian religion on the basis of demonstrative proofs of the existence of God and of the immortality of the human soul. The second statement, made in the First Meditation, claims that the primary purpose of the Meditations is the establishment of "unshakable" foundations of the sciences. Descartes compels the reader to determine whether the Meditations is primarily a work of Christian theology or a scientific treatise dedicated to establishing the certitude and indubitability of its primary concepts. The dissertation defends the view that only if the Meditations' "theological" purpose is understood to be subordinate to and in the service of advancing its "foundational" purpose is a coherent interpretation of the Meditations possible. ;The second goal of the dissertation is advanced through the study of the fundamental Cartesian theological and scientific principles in relation to "Cartesian doubt." These principles are shown to be advanced and defended by Descartes in order to establish the foundations of a comprehensive science of nature directed toward the unification of the human and the non-human order. The sought for derivation of the human from the non-human order is shown, however, to be in principle impossible on precisely Cartesian grounds. Cartesian "First Philosophy" demonstrates that what is "first for us" and what is "first by nature" are necessarily the same. The foundations of the sciences prove to be the very experiences of pre-scientific consciousness that are regarded as "patently false" by Cartesian doubt. The dissertation concludes with the suggestion that the possibility of philosophy itself is grounded in the unity and difference between pre-scientific "awareness" and scientific "cognition.". (shrink)

Einstein’s special theory of relativity has had a wide influence on fields far removed from physics. It has given the impression that physics has shown that there are now no absolute truths, that all beliefs are relative to the observer, and that traditional stable landmarks have been washed away. We each have our own frame of reference that is as good as any other frame, so that there are no absolute standards by which our actions may be judged. The predictions (...) of relativity theory, such as the elimination of simultaneity, the variation of mass with velocity, and the equivalence of mass and energy, are all highly counterintuitive and yet are precisely confirmed by detailed measurements. The clear rocklike mechanical physics of Newton seems to have dissolved into a swirling mist of unintelligible concepts, and familiar certainties seem to have disappeared. A detailed analysis of relativity theory shows, however, a completely different picture. Properly understood, it is a logical extension of Newtonian physics that expresses the relations of space and time in a more exact and elegant way and in the process shows forth more clearly the invariant features of the world. The apparently counterintuitive features appear as natural consequences that extend and refine our classical concepts. The traditional landmarks remain, but God’s world is more subtle than we had previously imagined. (shrink)

This essay places some conceptual pressure on the model of a “learning process” in Jürgen Habermas’s Auch eine Geschichte der Philosophie, and it asks whether this model introduces a subtle asymmetry into the relationship between religion and secular philosophy. Such an asymmetry would seem to obtain insofar as religious tradition is granted a privileged or unique status as the source of normative insights that are then available for rational scrutiny and translation into secular life. The essay also draws a comparison (...) between Lessing and Habermas: Lessing, like Habermas, saw revelation as a source of instruction for humanity, and affirmed that religion could thereby play a role in the Erziehung des Menschengeschlechts. But Lessing was careful to say that no valuable normative contents are found in religion that could not also be derived by secular reason alone. Habermas’s genealogy of post-metaphysical thinking does not seem to confirm Lessing’s idea; instead, it appears to confirm an asymmetry in the relation between religion and secular philosophy. (shrink)

Summary The pharmacological tradition in the medieval Islamic world developed on the basis of the Greek tradition, with the works of Dioscorides and Galen being particularly popular. The terminology was influenced not only by Greek, but also Middle Persian, Syriac, and indigenous Arabic words. Through recent research into Graeco-Arabic translations, it has become possible to discern the evolution of pharmacological writing in Arabic: in the late eighth century, the technical terms were being developed, with transliterations being used; by the mid-ninth (...) century, many standard Arabic translations for Greek words have been established. Various authors, however, expanded the pharmacology inherited from the Greeks. Galen had established a system of degrees of primary faculties (dry or moist, and warm or cold) that various physicians in the Islamic world modified. Al-Kindī, for instance, invented a theory of how to calculate these degrees in compound drugs, whereas ar-Rāzī criticised the epistemology that underlies Galen's theories. Ibn Sīnā (Avicenna) complemented the various degrees in his description of simple drugs. Furthermore, both Ibn Sarābiyun and al-Kaskarī integrated new drugs from the Islamic heartland, and the Far East into the Greek system. In these ways, the Arabic pharmacology developed in a creative tension of tradition and innovation. (shrink)

In his book A Secular Age, Charles Taylor appeals to the metaphysical?normative distinction between ?immanence? and ?transcendence? as definitive for post-Axial religion. On Taylor's view, therefore, those of us who embrace a fully secular modernity can be described as having abandoned ?transcendence? to take up our lives wholly within the confines of the immanent frame, though he grants we may seek alternative satisfactions or ?substitutes? for eternity. But the notion that any metaphysical?normative model of sacred experience can serve as an (...) irresistible foundation is open to doubt if one recalls the Heideggerian insight that any metaphysical picture both reveals and conceals aspects of our experience. Taylor's own description of sacred and non-sacred experience within the immanent frame seems to rely upon this foundational distinction, without entertaining the possibility that the language itself may very well actually distort what our experience is like. This paper pursues the above objections to Taylor's argument, focusing special attention on the assumption that one can judge aesthetic experience (such as listening to a Beethoven string quartet) with the criteria we have inherited from post-Axial religion. The overwhelming authority of the Axial tradition might seem to validate questions such as, ?Is there an object?? or ?Is the experience purely immanent?? But to such questions we might respond that such language simply has no grip on the phenomena. Any such talk of ?substitution? might therefore be understood as an historical remnant in Taylor's book of the traditional monotheist's critique of idolatry. (shrink)

This study examined some ethical implications of two different individual competitive orientations. Winning is crucially important in hypercompetitiveness , whereas a personal development (PD) perspective considers competition as a means to self-discovery and self-improvement. In a sample of 263 senior-level undergraduate business students, survey results suggested that hypercompetitiveness was generally associated with “poor ethics” and PD competitiveness was linked with “high ethics”. For example, hypercompetitive individuals generally saw nothing wrong with self-interested gain at the expense of others, but PD competitors (...) viewed such activities as largely inappropriate. Hypercompetitive people also tended to be highly Machiavellian but not ethically idealistic. In contrast, PD competitors tended to be ethically idealistic but not Machiavellian. Managers that are interested in both high ethics and high functioning work groups may wish to consider the potential importance of attempting to channel hypercompetitive tendencies into PD directions. (shrink)